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The organic chemistry of drug design and drug

The organic chemistry of drug design and drug

The organic chemistry of drug design and drug action by Richard B. Silverman

The organic chemistry of drug design and drug action



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The organic chemistry of drug design and drug action Richard B. Silverman ebook
Format: pdf
Publisher: Academic Press
ISBN: 0126437327, 9780126437324
Page: 646


It is contrasted by a reductionist approach , . Derek Lowe, an Arkansan by birth, got his BA from Hendrix College and his PhD in organic chemistry from Duke before spending time in Germany on a Humboldt Fellowship on his post-doc. The term is loosely used in science to refer to a inter-disciplinary field of study that relies on biology, mathematics, statistics, chemistry, and bioinformatics to describe the dynamic interplay life's elements. Donald Watson, assistant professor of chemistry and biochemistry at UD, is part of a research team that has discovered an easier method for incorporating fluorine into organic molecules, giving chemists an important new tool in developing materials ranging from new medicines to agricultural chemicals. The task in targeted therapy was to identify a key protein that is overactive, overproduced, or somehow altered in cancer cells, and then design a drug that will bind to that protein and inhibit its action. He says players are now working on the ground-up design of a protein that would act as an inhibitor of the influenza A virus, and he expects to expand the drug development uses of the game to small molecule design within the next year. Reader's Corner: Cheap and Effective TB Drug Being Ignored? This is a one-drug, one-protein model. UD prof helps discover new chemical method important to drug design, agrichemicals. OTC-pharmacy A reader brought an interesting issue to our attention: mainstream medicine is rejecting a lifesaving tuberculosis Johnson & Johnson's new drug designed to treat multi-drug-resistant tuberculosis, benaquline, was given accelerated approval despite the FDA's findings that the drug comes with a fivefold greater risk of death compared to a placebo. The organic chemistry of drug design and drug action - Google Books This book represents a new approach based on physical organic chemical principles.

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